![]() These include Gordon Setters, Irish Wolfhounds, Brittany Spaniels, Golden Retrievers, and Doberman Pinschers. "Certain breeds of dogs, especially large breeds, are at greater risk of developing fibrosarcoma."Ĭertain breeds of dogs, especially large breeds, are at greater risk of developing fibrosarcoma. Sarcomas have long been associated with injection sites in cats (e.g., feline post-vaccinal fibrosarcomas see handout "Post-Vaccination Sarcoma in Cats" for more information), but there is growing evidence that tumors may be associated with injection sites in dogs too. In the case of fibrosarcomas, although no specific risk factors or cause have been identified, sarcomas in general (tumors of the connective tissue) have been associated with radiation, trauma, foreign bodies, and orthopedic implants. Most seem to be caused by a complex mix of risk factors, some environmental and some genetic or hereditary. Very few tumors and cancers have a single known cause. The reason why a particular dog may develop this, or any tumor or cancer, is not straightforward. Fibrosarcomas are usually slow growing, except for those of the leg bones, which can grow very rapidly. In rare cases, fibrosarcomas will originate within the jaw bones, or leg bones, causing a primary form of bone cancer. ![]() They can also be found in the nasal cavity or mouth (sometimes invading the jaw bones). They are most commonly found on the limbs (often the extremities) and the trunk of the body. Fibrosarcomas occur most often in the connective tissue of the skin and beneath the skin.Ī fibrosarcoma is a type of soft tissue sarcoma (see handout "Soft Tissue Sarcomas"). Fibroblasts are the most common cells of the connective tissue in the body (the tissue that connects, supports, and binds or separates tissues and organs). The results of this retrospective study indicate that many spindle cell tumours managed in first opinion practice exhibit a low-grade biological behaviour and may respond well to more conservative surgery than current recommendations advise.A fibrosarcoma is a malignant tumor that develops from the uncontrolled overgrowth of cells called fibroblasts. A palpable assessment of tumour invasion into underlying tissues was significantly associated with decreased disease-free interval (P<0.0001) and survival time (P = 0.0070). Tumour size, location or degree of surgical resection were not significantly related to survival or tumour recurrence. Most deaths were unrelated to sarcoma (50 dogs, 60.2 per cent) or unknown (15 dogs, 18 per cent). Eighteen dogs (21.7 per cent) died of tumour-related causes. Tumours recurred locally in 29 dogs (27.9 per cent). Excision margins of 3 cm or more were described in less than 10 per cent of cases. The method of surgical resection was described as marginal in 45 dogs (44.2 per cent). Questionnaires were sent to the submitting veterinarians, requesting details about the tumour, surgery performed and ultimate outcome of the patient. ![]() To define the outcome of a cohort of canine patients with a histological diagnosis of spindle cell tumour of soft tissue managed solely by surgery in first opinion practice.Ĭlinical details of 104 spindle cell sarcomas submitted to Finn Pathologists during the year 2000 were reviewed. ![]()
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